Genome-wide characterization of recombination partner choice of homologs and sister chromatids
- CRISPR screen + single-cell sequencing (sci-L3-WGS/target-seq/Strand-seq)
- Yeast, mouse, human etc.
Genome-wide mapping of heteroduplex DNA
- Single-cell sequencing (sci-L3-MC)
Systematically investigate effect from tissue-of-origin on genome instability
- Single-cell sequencing (sci-L3-DNA/RNA co-assay)
- Worm, fly, mouse etc.
Construct dense linkage maps in non-model organisms
- Single-cell sequencing (sci-L3-WGS)
- Non-human primates etc.
DNA repair gene finding in unculturable microbes