Research
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Genome-wide characterization of recombination partner choice of homologs and sister chromatids
- CRISPR screen + single-cell sequencing (sci-L3-WGS/target-seq/Strand-seq)
- Yeast, mouse, human etc.
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Genome-wide mapping of heteroduplex DNA
- Single-cell sequencing (sci-L3-MC)
- Yeast
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Systematically investigate effect from tissue-of-origin on genome instability
- Single-cell sequencing (sci-L3-DNA/RNA co-assay)
- Worm, fly, mouse etc.
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Construct dense linkage maps in non-model organisms
- Single-cell sequencing (sci-L3-WGS)
- Non-human primates etc.
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DNA repair gene finding in unculturable microbes